Programmed cell death and human embryo fragmentation

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Programmed cell death and human embryo fragmentation.

The quality of embryos produced by in-vitro fertilization (IVF) is variable. Many embryos contain unequal sized blastomeres and multiple cellular fragments. Embryos with excessive fragmentation have limited developmental potential both in vitro and in vivo. Histologically, some blastomeres of fragmented embryos resemble cells undergoing apoptosis as a result of programmed cell death (PCD). The ...

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ژورنال

عنوان ژورنال: Molecular Human Reproduction

سال: 1996

ISSN: 1360-9947,1460-2407

DOI: 10.1093/molehr/2.2.93